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Lifestyle interventions

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  1. 26 november 2020 bij 17:35- Antwoorden

    Nice study, your study appears to confirm previous small nutritional intervention studies showing that proteins are more beneficial for your liver. I was wondering whether dietary fiber could have been a confounder?

    • E. Winters-van Eekelen (Leiden) 26 november 2020 bij 17:54- Antwoorden

      Thank you for your interest! Indeed, there have been multiple (small) intervention studies investigating the role of macronutrients in liver fat accumulation. We have just published a systematic review and meta-analysis to summarize all this evidence, which shows that protein indeed appears to be benificial for your liver when content when replacing carbohydrates (

      With regard to your question: yes, dietary fiber might well be a confounder in this association. In our substitution models we have adjusted for all energy-yielding nutrients, among which fiber and alcohol, thereby attemping to mitigate this potential confounding.

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